Bloodborne Wiki
Blood Dreg
Blood Dreg
Max No. Held 99
Max Stored 99
Usage Type Finite
QS Bullet Use QS Bullet Use -
Attribute Bonus
Strength - Skill - Bloodtinge - Arcane -
Attribute Requirement
Strength - Skill - Bloodtinge - Arcane -
Looted from adversarial Hunters (or NPC Hunters).
Notes Can be given to Annalise, Queen of the Vilebloods for a gesture.

A Blood Dreg is a consumable in Bloodborne.


In-Game Description

The Vilebloods of Cainhurst, blood-lusting hunters, see these frightful things in coldblood.
They often appear in the blood of echo fiends, that is to say, the blood of hunters. Queen Annalise partakes in these blood dregs offerings, so that she may one day bear the Child of Blood, the next Vileblood heir.


Blood Dregs can only drop while the Corruption Rune is equipped:


  • Blood Dregs can be given to Annalise, Queen of the Vilebloods and in return she rewards with gestures. After giving her at least one dreg, the player is rewarded with the Deep Respect gesture. The amount of dregs the player offers is accumulated and determines your rank in the Vileblood Register.
  • Using a Blood Dreg grants the player +1 Insight.


  • Players only need to give one Blood Dreg to Annalise to acquire the Deep Respect gesture from her, which means that aside from online play, it becomes functionally worthless from then on out. Players can simply use the Blood Dregs as if they were Madman's Knowledge.
    • This, in turn, makes the Corruption rune very worthwhile in subsequent playthroughs, as it means players will always have the opportunity to get plenty more insight from outside Chalice Dungeons.


  • Blood Dregs resemble sperm cells, the male sex cell that is used in reproduction. It is possible that it is actual sperm cells, and Annalise is trying to make herself pregnant through them, thus having an heir to the Cainhurst line.
  • The Japanese name for this item is '血の穢れ', which means 'Impurity of Blood' or 'Blood's Impurity'.
    • Cainhurst's Oath Rune, in Japanese, is '穢れ'.
    • In Japan's native religion Shinto, '穢れ' is 'obtained' by coming into contact with, generally, unclean things such as death and blood. It is apt, then, that Hunters would have this in their blood.
      • That said, nearly all NPCs drop this, which would mean all humans or, at least, all Yharnamites, are 'tainted'. This may be due to the practice of blood transfusion being commonplace, as contact with blood would also cause '穢れ'.